At what stage can we say that loneliness has reached a state of insanity?
unhappy as a result of being without the companionship of others: a lonely man
causing or resulting from the state of being alone: a lonely existence
isolated,...
Hmm, I love the word called Insanity. Source of power when it leash well enough. The last one, Solitary loneliness. I would say only loneliness cannot drive someone to reach insanity, need more factor to be presented